| 产品详情 |
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| Antigenic Specificity | LRRTM3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LRRTM3 Polyclonal Antibody. The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the Abeta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma Abeta42 levels, suggesting that LRRTM3 is a functional and positional |
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| Immunogen | n/a |
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| Other Names | UNQ803/PRO1693; leucine-rich repeat transmembrane neuronal protein 3 |
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| Gene, Accession # | Entrez: 216028, 294380, 347731; Uniprot: D3ZAL8, Q86VH5, Q8BZ81 |
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| Catalog # | PA5-21098 |
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| Price | |
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| Order / More Info | LRRTM3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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