产品详情 |
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Antigenic Specificity | CD80 |
Clone | 2D10 |
Host Species | Mouse |
Reactive Species | human, cross-reactivity: rhesus |
Isotype | IgG1, κ |
Format | PE-Cy7 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Cy7 anti-human CD80. CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation. |
Immunogen | n/a |
Other Names | B7-1, B7, BB1 |
Gene, Accession # | Gene ID: 941 |
Catalog # | 305218 |
Price | |
Order / More Info | CD80 Antibody from BIOLEGEND |
Product Specific References | PubMed: 18316378,22312112,23429540 |
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