| 产品详情 |
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| Antigenic Specificity | MYOC |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:200-1:500, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MYOC Polyclonal Antibody. Myocilin is an extracellular protein expressed in the eye, including the retina, trabecular meshwork and ciliary body. Myocilin can form homomultimers in vivo and can also associate with components of the ECM via interactions with the Hep II domain of FibroPVRL1. In addition, myocilin interacts with myosin regulatory light chain, a component of the myosin motor protein complex. This interaction implies a role for myocilin in the actomyosin system, linking myocilin to the functional status of the trabecular meshwork (TM), which is responsible for controlling the intraocular pressure (IOP). Alterations in functions of the TM may lead to IOP elevation and development of glaucoma, a major cause of blindness. Myocilin i |
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| Immunogen | n/a |
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| Other Names | Myocilin, Myocilin 55 kDa subunit, Trabecular meshwork-induced glucocorticoid response protein, MYOC, GLC1A, TIGR |
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| Gene, Accession # | Entrez: 4653; Uniprot: Q99972 |
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| Catalog # | PA5-55590 |
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| Price | |
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| Order / More Info | MYOC Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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