产品详情 |
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Antigenic Specificity | CD81 |
Clone | QV-6A8 |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2b |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | flow cytometry, CELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins. CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry. |
Immunogen | cDNA |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | GM-1113 |
Price | |
Order / More Info | CD81 Antibody from ALDEVRON FREIBURG GmbH |
Product Specific References | n/a |
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