| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | RELA / NFKB p65, pSer536 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA (1:500 - 1:3000), IHC, IHC-P (1:50 - 1:250), WB (1:100 - 1:1000) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | RELA / NFKB p65 Antibody (phospho-Ser536) LS-C42658. Detects the p65 (RelA) subunit of nuclear factor kappa-B (NFkB) when phosphorylated at serine 536. NFkB is a heterodimeric DNA binding protein which was originally identified consisting of p65 and p50 (NFkB1) subunits. Research has led to the discovery of other subunits, including p52 (NFkB2), cRel, and RelB. NFkB is ubiquitously expressed, and functions as a second messenger which upon activation leads to the transcription of a number of genes. NFkB is activated by a number of agents, including pro-inflammatory cytokines and bacterial lipopolysaccharide, and is essential for the maturation of T cells and regulation of their survival and activation. Phosphorylation of serine 536 contributes to NFkB transactivation and increases p65 transcription activity. |
|---|
| Immunogen | Synthetic peptide corresponding to residues surrounding serine 536 of human NFkB p65 protein. ( pSer536 ). |
|---|
| Other Names | RELA, NF-kappa-B p65delta3, NFKB3, p65, Transcription factor p65 |
|---|
| Gene, Accession # | RELA, Gene ID: 5970 |
|---|
| Catalog # | LS-C42658 |
|---|
| Price | |
|---|
| Order / More Info | RELA / NFKB p65, pSer536 Antibody from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|