产品名称 CD14 Antibody from ATGen
产品货号 ATGA0339
产品价格 现货询价,电话:010-67529703
产品规格 100ul, 50ul
产品品牌 ATGen
产品概述
产品详情
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Antigenic SpecificityCD14
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, k
Formatpurified
Size100ul, 50ul
Concentrationn/a
ApplicationsELISA, WB, Flow cytometry
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DescriptionThe protein encoded by this gene is a component of the innate immune system. CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol tail (mCD14), the other a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48kDa) or is directly secreted from intracellular vesicles (56kDa).The x-ray crystal structure of human CD14 reveals a monomeric, bent solenoid structure containing a hydrophobic amino-terminal pocket. CD14 was the first described pattern recognition receptor. CD14 acts as a co-receptor (along with the Toll-like receptor TLR4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns such as lipoteichoic acid.
ImmunogenRecombinant human CD14 (20-349aa) purified from E.coli.
Other Namesmonocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
Gene, Accession #NP 001167576
Catalog #ATGA0339
Price
Order / More InfoCD14 Antibody from ATGen
Product Specific Referencesn/a
产品资料