| 产品详情 |
| Edit |   |
| Antigenic Specificity | BRCA1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat, human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | n/a |
| Concentration | n/a |
| Applications | ELISA (1:500 - 1:1000), WB (1:100 - 1:500) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | BRCA1 Antibody LS-C413739. Specificity: Breast cancer type 1 susceptibility protein (BRCA1) plays a central role in DNA repair by facilitating cellular response to DNA repair. BRCA1 is required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. BRCA1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in BRCA1 are a cause of genetic susceptibility to breast and ovarian cancers. |
| Immunogen | KLH-conjugated synthetic peptide from the N-terminal region of human BRCA1. |
| Other Names | BRCA1, BROVCA1, BRCC1, Breast cancer 1, early onset, PPP1R53, PSCP, PNCA4, RING finger protein 53, RNF53, BRCAI, Breast cancer 1 early onset, IRIS |
| Gene, Accession # | BRCA1, Gene ID: 672 |
| Catalog # | LS-C413739 |
| Price | |
| Order / More Info | BRCA1 Antibody from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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