产品详情 |
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Antigenic Specificity | Acetylated Lysine |
Clone | 15G10 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-Acetylated Lysine. Proteins are reversibly and dynamically acetylated on the ε-amino group of lysine by acetyltransferases and deacetylated by deacetylases. This post-translational modification can regulate protein function (interactions with other proteins and DNA binding). Histones and transcription factors (PCAF, p53, p300, etc) appear to be the major targets of acetyltransferases. Acetylation is usually associated with chromatin remodeling and transcriptional activation, although in some cases (telomeres) it is associated with gene silencing. The 15G10 antibody recognizes acetylated lysine residues on proteins. |
Immunogen | Acetylated protein mixture |
Other Names | n/a |
Gene, Accession # | Gene ID: 8850 |
Catalog # | 623406 |
Price | |
Order / More Info | Acetylated Lysine Antibody from BIOLEGEND |
Product Specific References | PubMed: 20145209 |
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