产品名称 ADAR1 Antibody from BIOLEGEND
产品货号 685901
产品价格 现货询价,电话:010-67529703
产品规格 25 µg
产品品牌 BIOLEGEND
产品概述
产品详情
Edit&nbsp
Antigenic SpecificityADAR1
Clone15.8.6
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG
Formatpurified
Size25 µg
Concentrationn/a
ApplicationsWestern Blot (WB), ICC, KO/KD-Western Blot (WB), IHC-P
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPurified anti-ADAR1. Adenosine deaminases acting on RNA (ADARs) are involved in RNA editing that converts adenosine residues to inosine in double-stranded RNAs (dsRNAs). The translation machinery reads inosine as guanosine, leading to recoding of a relatively small number of neurotransmitter and ion channel genes and diversification of their functions. Three ADAR gene family members (ADAR1-3) are known in vertebrates. Members of the ADAR gene family share common structural features, such as the presence of multiple dsRNA binding domains (dsRBDs) and a separate deaminase domain. Three repeats of dsRBD are present in ADAR1, while only two repeats are found in ADAR2 and ADAR. ADAR1 increases the rate of pre-microRNA cleavage by Dicer and facilitates loading of miRNA onto RNA-induced silencing complexes. ADAR1 differentiates its functions in RNA editing and RNAi by formation of either ADAR1/ADAR1 homodimer or Dicer/ADAR1 heterodimer complexes. The deficiency of ADAR1 embryonically lethal due to overall apoptosis.
ImmunogendsRNA binding domain
Other NamesDRADA, Double-stranded RNA-specific adenosine deaminase, p136, IFI-4
Gene, Accession #Gene ID: 103
Catalog #685901
Price
Order / More InfoADAR1 Antibody from BIOLEGEND
Product Specific Referencesn/a
产品资料