产品详情 |
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Antigenic Specificity | ADAM10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 0.5 mg/ml |
Applications | Western blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ADAM10 Antibody. Proinflammatory cytokine tumor necrosis factorα (TNF-α) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-α, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-α, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned a |
Immunogen | Synthetic peptide corresponding to residue surrounding amino acid 735 of human ADAM10 |
Other Names | MADM , CDw156, CD156c , kuz , EC 3.4.24.81, HsT18717 |
Gene, Accession # | Gene ID: 2393947, Accession: AAC51766 |
Catalog # | 3201-100 |
Price | |
Order / More Info | ADAM10 Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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