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Product Name | Acalabrutinib |
Description | Acalabrutinib (ACP-196) is an orally available, selective irreversible inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. It is a second generation BTK inhibitor with improved pharmacological properties with better plasma exposure, oral absorption and shorter half-life. It prevents the activation of B-cell antigen receptor (BCR) signaling pathway, thus preventing B-cell activation and BTK mediated activation of downstream survival pathways. MW: 465.52. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide; ACP-196 |
Gene, Accession, CAS # | CAS: 1420477-60-6 |
Catalog # | B1193-25 |
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Order / More Info | Acalabrutinib from BIOVISION, INC. |
Product Specific References | n/a |
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