| 产品详情 |
| Edit |   |
|---|
| Product Name | A-804598 |
|---|
| Description | A potent and selective competitive antagonist of the P2X7 receptor (IC50s = 9.9 and 10.9 nM in 132N1 cells transfected with the rat or mouse receptor, respectively), inhibits IL-1β release in LPS and IFN-γ-stimulated THP-1 cells (IC50 = 8.5 nM); selective over other P2X and P2Y receptors at concentrations up to 100 µM; prevents footshock-induced increases in IL-1β mRNA in the rat hypothalamus , |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | P2X-7 A804598 IL1β IL1b P2-X Y THP1 IFNγ lipopolysaccharide IFNg GPCR interleukin |
|---|
| Gene, Accession, CAS # | CAS: 1125758-85-1 |
|---|
| Catalog # | 20060-5 |
|---|
| Price | |
|---|
| Order / More Info | A-804598 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|