| 产品详情 |
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| Antigenic Specificity | CD71 / Transferrin Receptor |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG2a |
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| Format | biotin conjugate |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:1 - 1:10), IHC, IHC-Fr |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD71 / Transferrin Receptor Antibody (Biotin) LS-C43740. Recognizes rat CD71, also known as transferrin receptor, a homodimeric type II transmembrane protein, expressed by all proliferating cells and cells with a requirement for iron, including reticulocytes and capillary endothelium in brain. Clone 0X-26 also binds to a number of non-dividing normal tissues. The balance between a sufficient amount of iron uptake and prevention of accumulation of excess iron within a cell, is vitally important to maintain cellular functions such as oxygen and electron transport and mitochondrial energy metabolism, whilst preventing permanent cell and tissue damage. Transferrin receptor (CD71), transferrin and ferritin have been identified as specialized proteins which control the uptake, transport and storage of free iron in tissues, thereby maintaining iron homeostasis. An imbalance in iron homeostasis within the brain has been linked with the neurodegenerative diseases, Alzheimer's?™s, Parkinson's, Huntington's and Multiple Sclerosis. Is reported as suitable for use in immunoelectron microscopy. OX-26 detects a band of ~95kD in Western blotting under reducing conditions and ~195kD under non-reducing conditions reflecting it's homodimeric structure. |
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| Immunogen | PHA activated rat lymphocytes. |
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| Other Names | TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1 |
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| Gene, Accession # | TFRC, Gene ID: 7037 |
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| Catalog # | LS-C43740 |
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| Price | |
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| Order / More Info | CD71 / Transferrin Receptor Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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