| 产品详情 |
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| Antigenic Specificity | TNNC1 / Cardiac Troponin C |
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| Clone | 1A2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | affinity purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TNNC1 / Cardiac Troponin C Antibody (clone 1A2) LS-C58314. Recognizes human Troponin C, an 18kD subunit of the Troponin complex found on actin filaments in muscle tissue. Troponin C (TnC) is responsible for binding calcium ions. In the absence of calcium, TnC has an inhibitory action on the actin filaments. When calcium binds to TnC, a conformational change takes place in Troponin I, which in turn causes a change in another associated protein, tropomyosin. Troponin and tropomyosin is repositioned away from the actin filaments, leaving the myosin binding sites available for cross-bridges to form and muscle contraction to occur. Recognizes free cardiac Troponin C and TnC in binary complex with cardiac Troponin I. The antibody does not recognize free cardiac Troponin I or cardiac Troponin T. May be used as a capture antibody in ELISA assays for human Troponin C. |
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| Immunogen | Human slow skeletal troponin C. |
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| Other Names | TNNC1, CMD1Z, Cardiac troponin C, CMH13, Troponin C type 1 (slow), TN-C, TNNC, Troponin C, slow, Troponin C1, slow |
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| Gene, Accession # | TNNC1, Gene ID: 7134 |
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| Catalog # | LS-C58314 |
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| Price | |
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| Order / More Info | TNNC1 / Cardiac Troponin C Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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