| 产品详情 |
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| Antigenic Specificity | Troponin Complex (Cardiac) |
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| Clone | 20C6 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | affinity purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Troponin Complex (Cardiac) Antibody (clone 20C6) LS-C58311. Recognizes human troponin, a complex of three proteins integral to muscle contraction. The three-unit troponin complex (Troponin I, T and C), bound to tropomyosin, is located on the actin filament of skeletal and cardiac muscle. Troponin T binds to tropomyosin to form the troponin-tropomyosin complex. Troponin C binds calcium ions to produce a conformational change in Troponin I. Troponin I binds to the actin in thin myofilaments to hold the troponin-tropomyosin complex in place. When calcium binds to troponin, a conformation change is forced in troponin and tropomyosin, moving both proteins away from the myosin binding sites on the actin filaments. Thus, myosin can bind to actin and muscle contraction occurs. Recognizes the native troponin complex. It does not cross-react with any of the individual components Troponin I, T or C. |
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| Immunogen | Human native troponin complex. |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | LS-C58311 |
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| Price | |
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| Order / More Info | Troponin Complex (Cardiac) Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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