| 产品详情 |
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| Product Name | PROGESTERONE ELISA |
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| Description | In the Progesterone ELISA Assay Kit, the (Antigens) in the sample competes with the Antigensic Progesterone conjugated with horseradish peroxidase (HRP) for binding to the limited number of antibodies anti Progesterone coated on the microplate (solid phase). After incubation, the bound/free separation is performed by a simple solid-phase washing. Then, the enzyme HRP in the bound-fraction reacts with the Substrate (H2O2) and the TMB Substrate and develops a blu color that changes into yellow when the Stop Solution (H2SO4) is added. The colour intensity is inversely proportional to the Progesterone concentration of in the sample. Progesterone concentration in the sample is calculated through a calibration curve. Sample Types: serum, plasma. Range:.2 - 40 ng/ml. Sensitivity: 0.05 ng/mL. Time: 1.5 hours • Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy (supports gestation) and embryogenesis of humans and other species. Progesterone is the major naturally occurring human progestagen. Progesterone is important for aldosterone (mineralocorticoid) synthesis, as 17-hydroxyprogesterone is for cortisol (glucocorticoid). Progesterone levels are relatively low in children and postmenopausal women. Adult males have levels similar to those in women during the follicular phase of the menstrual cycle. In women, progesterone levels are relatively low during the preovulatory phase of the menstrual cycle, rise after ovulation, and are elevated during the luteal phase. If pregnancy occurs, progesterone levels are maintained at luteal levels initially. After delivery of the placenta and during lactation, progesterone levels are very low. The fall in progesterone levels following delivery is one of the triggers for milk production. Progesterone is produced in the adrenal glands, the gonads (specifically after ovulation in the corpus luteum), the brain, and, during pregnancy, in the placenta. Progesterone converts the endometrium to its secretory stage to prepare the uterus for implantation. If pregnancy does not occur, progesterone levels will decrease, leading, in the human, to menstruation. Progesterone belongs to the group of neuroSteroid that are found in high concentrations in certain areas in the brain and are synthesized there. NeuroSteroid affect synaptic functioning, are neuroprotective, and affect myelinization. Progesterone has multiple effects outside of the reproductive system. Progesterone is thermogenic, it reduces spasm and relaxes smooth muscle. Bronchi are widened and mucus regulated. Progesterone acts as an antiinflammatory agent and regulates the immune response. Progesterone also assists in thyroid function, in bone building by osteoblasts. Measurement of serum progesterone concentrations have been used in evaluating ovarian function. |
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| Size | 1 x 96 well |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Progesterone,steroid hormones, C-21 steroid hormone |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | DCM006 |
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| Order / More Info | PROGESTERONE ELISA from EAGLE BIOSCIENCES INC. |
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| Product Specific References | n/a |
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