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Product Name | Bgn, 38-369aa, Mouse, hIgG-His-tag, Baculovirus |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. Bgn, also known as biglycan preproprotein, is a small leucine-rich repeat proteoglycan (SLRP). It binds to the growth factors BMP-4 and influences BMP-4 bioactivity. It plays an important role in stabilizing fibrotic scars after experimental myocardial infarction. It may function in connective tissue metabolism by binding to collagen fibrils and TGF-beta and may promote neuronal survival. Its ablation improves cardiac function and attenuates left ventricular hypertrophy and fibrosis after long-term pressure overload. It is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Recombinant mouse Bgn, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Size | 250ug, 50ug, 10ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Biglycan, Bgn, BG, DSPG1, PG-S1, PGI, SLRR1A |
Gene, Accession, CAS # | NP 031568 |
Catalog # | ATGP3775 |
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Order / More Info | Bgn, 38-369aa, Mouse, hIgG-His-tag, Baculovirus from ATGen |
Product Specific References | n/a |
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