| 产品详情 |
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| Antigenic Specificity | CD144 / CDH5 / VE Cadherin |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, human |
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| Isotype | n/a |
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| Format | Protein G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, IF, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD144 / CDH5 / VE Cadherin Antibody LS-C500157. Specificity: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction. |
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| Immunogen | Recombinant Human Cadherin-5 protein (349-569AA) |
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| Other Names | CDH5, 7B4, 7B4 antigen, CD144, Cadherin-5, Endothelial-specific cadherin, Vascular endothelial cadherin, VE-cadherin, VEC, CD144 antigen, VE Cadherin |
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| Gene, Accession # | CDH5, Gene ID: 1003 |
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| Catalog # | LS-C500157 |
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| Price | |
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| Order / More Info | CD144 / CDH5 / VE Cadherin Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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