产品名称 CD31 Antibody from DIANOVA GmbH
产品货号 DIA-310
产品价格 现货询价,电话:010-67529703
产品规格 500 µl
产品品牌 DIANOVA GmbH
产品概述
产品详情
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Antigenic SpecificityCD31
CloneSZ31
Host SpeciesRat
Reactive Speciesmouse, pig,
IsotypeIgG2a
Formatpurified
Size500 µl
Concentrationn/a
ApplicationsIHC, Paraffin Sections (FFPE), Western Blot
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DescriptionAntibody clone SZ31 is the first antibody which reacts specifically with murine CD31 in formalin-fixed paraffin-embedded tissue sections. Does not crossreact with rat or human. Studies have shown CD31 to be a superior marker in human angiogenesis, which reportedly predicts tumor recurrence. Pathophysiological studies of CD31 in murine model systems had limitations because standard formalin-fixed sections were excluded. The clone SZ31 eliminates these restrictions by allowing high quality immunohistochemical analysis of standard formalin-fixed paraffin sections in mice.
ImmunogenMurine amino acid fragment (amino acids 610-681 of mouse CD31)
Other NamesPECAM-1, CD31
Gene, Accession #Pecam1, 18613
Catalog #DIA-310
Price
Order / More InfoCD31 Antibody from DIANOVA GmbH
Product Specific ReferencesCardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury. Holscher M, Silter M, Krull S, von Ahlen M, Hesse A, Schwartz P, Wielockx B, Breier G, Katschinski DM, Zieseniss A. J.Biol.Chem. 286: 11185-11194, 2011. Placental vasculogenesis is regulated by keratin-mediated hyperoxia in murine decidual tissues. Kroger C, Vijayaraj P, Reuter U, Windoffer R, Simmons D, Heukamp L, Leube R, Magin TM. Am.J.Pathol. 178(4): 1587-1590, 2011. NAHA, a Novel Hydroxamic Acid-Derivative, Inhibits Growth and Angiogenesis of Breast Cancer In Vitro and In Vivo. Jiang J, Thyagarajan-Sahu A, Krch?ak V, Jedinak A, Sandusky GE, et al. PLoS ONE 7(3): e34283, 2012. Reduces Spontaneous Metastatic Spread of Prostate Cancer in the TRAMP. Copeland BT, Bowman MJ, Ashman LK. Genetic Ablation of the Tetraspanin CD151 Model. Mol Cancer Res. 11(1):95-105, 2013. Therapeutic ef-fect of lenalidomide in a novel xenograft mouse model of human blastic NK cell lymphoma/blastic plasmacytoid dendritic cell neoplasm. Agliano A, Martin-Padura I, Marighetti P, Gregato G, Calleri A, Prior C, Redrado M, Calvo A, Bertolini F. Clin Cancer Res. 1;17(19):6163-73, 2011. Absence of IL-12R?2 in CD33(+)CD38(+) pediatric acute myeloid leukemia cells favours progression in NOD/SCID/IL2R?C-deficient mice. Ferretti E, Montagna D, Di Carlo E, Cocco C, Ribatti D, Ognio E, Sorrentino C, Lisini D, Bertaina A, Locatelli F, Pistoia V, Airoldi I. Leukemia 26(2):225-35, 2012.
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