| 产品详情 |
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| Product Name | ALDOSTERONE ELISA |
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| Description | The principle of this Aldosterone ELISA Assay Kit follows the typical competitive binding scenario. Competition occurs between an unlabeled Antigens (present in calibrators, control and patient samples) and an enzyme-labelled Antigens (conjugate) for a limited number of antibody binding site on the microwell plate. The washing steps remove unbound materials. After the washing step, the enzyme substrate (TMB) is added. The enzymatic reaction is terminated by addiction of the Stop Solution. The intensity of the color is inversely proportional to the concentration of Aldosterone in the sample. The absorbance is measured on a microtiter plate reader. A set of calibrators is used to plot a calibration curve from which the amount of Aldosterone in samples and controls can be directly read. Sample Types: serum, plasma. Range: 20 - 2000 pg/ml. Sensitivity: 7 pg/ml. Time: 1.5 hours • Aldosterone is a steroid hormone produced by the adrenal cortex in the adrenal gland, is the most potent mineralocorticoid in humans, it regulate sodium and potassium balance in the blood. Aldosterone secretion appears to be stimulated primarily through the renin-angiotensin system. Acting on mineralocorticoid receptors (MR) on principal cells in the collecting ducts of the kidneys, it increases the permeability of their apical (luminal) membrane to potassium and sodium and activates their basolateral Na+/K+ pumps, stimulating ATP hydrolysis, reabsorbing sodium (Na+) ions and water into the blood, and excreting potassium (K+) ions into the urine. Aldosterone regulate plasma bicarbonate (HCO3-) levels and its acid/base balance. Aldosterone is responsible for the reabsorption of about 2% of filtered sodium in the kidneys. |
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| Size | 1 x 96 well |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | aldosterone |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | DCM053 |
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| Order / More Info | ALDOSTERONE ELISA from EAGLE BIOSCIENCES INC. |
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| Product Specific References | n/a |
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