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Antigenic Specificity | ABAT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100µg |
Concentration | n/a |
Applications | ELISA, WB, IHC, IP • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-ABAT polyclonal antibody. 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alte |
Immunogen | 4-aminobutyrate aminotransferase |
Other Names | ABAT, FLJ17813, GABA aminotransferase, GABA AT, GABA T, GABA transaminase, GABAT, L AIBAT |
Gene, Accession # | Gene ID: 18, UniProt: P80404 |
Catalog # | FNab00026 |
Price | |
Order / More Info | ABAT Antibody from FINETEST |
Product Specific References | n/a |
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