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| Product Name | FES, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). FES is a protooncogene that encodes a protein-tyrosine kinase distinct from c-Src, c-Abl and other nonreceptor tyrosine kinases. FES was originally identified as the cellular homolog of several transforming retroviral oncoproteins. FES plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell-cell interaction. Genetic analysis using transgenic mouse model implicate FES in the regulation of inflammation and innate immunity. FES modulates the innate immune response of macrophages to LPS challenge, in part, by regulating the internalization and down-regulation of the TLR4 receptor complex. Source: Recombinant protein corresponding to human FES, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~125kD Specific Activity: 56nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FES, Recombinant, Human, GST-Tag (Tyrosine-protein Kinase Fes/Fps, Feline Sarcoma/Fujinami Avian Sarcoma Oncogene Homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, FPS) |
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| Gene, Accession, CAS # | Accession: NM_002005 |
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| Catalog # | 499983 |
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| Order / More Info | FES, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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