产品详情 |
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Product Name | 17-AAG |
Description | Purity >98% by HPLC. HSP90 inhibitor that displays a 100-fold higher affinity for HSP90 derived from tumour cells compared to HSP90 from normal cells. Because Hsp90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis and oncogenesis, it obstructs the proliferation of cancer cells and shows anti-cancer activity in experimental animals. More stable and less toxic analog of Geldanamycin. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | [(3R,5R,6S,7R,8E,10R,11R,12E,14Z)-6-hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate [(3R,5R,6S,7R,8E,10R,11R,12Z,14E)-6-hydroxy-5,11-dimethoxy-3,7,9,15 |
Gene, Accession, CAS # | CAS: 75747-14-7 |
Catalog # | LS-H11817 |
Price | |
Order / More Info | 17-AAG from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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