产品名称 alpha-2-macroglobulin (porcine) Antibody from PENINSULA LABORATORIES INTERNATIONAL, INC.
产品货号 T-3512.0200
产品价格 现货询价,电话:010-67529703
产品规格 200 ug
产品品牌 PENINSULA LABORATORIES INTERNATIONAL, INC.
产品概述
产品详情
Edit&nbsp
Antigenic Specificityalpha-2-macroglobulin (porcine)
ClonePAM-F101
Host SpeciesMouse
Reactive Speciesporcine
IsotypeIgG1
Formataffinity purified
Size200 ug
Concentrationn/a
ApplicationsIHC, WB
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionClone PAM-F101 is a unique monoclonal antibody developed against porcine α-2-Macroglobulin. α-2-Macroglobulin (α2M) is a broad spectrum proteinase inhibitor synthesized mainly by hepatocytes, and locally by macrophages. The inhibitory mode of action uses a capturing mechanism through a peptide sequence (``bait region'') which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change and concomitant thioester bond hydrolysis is induced, leading to covalent binding of α2M to the proteinase. The bound enzyme remains active against low molecular weight substrates while the activity against high molecular weight substrates is reduced. The proteinase-α2M complex is recognized by macrophage receptors and cleared from the system
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #T-3512.0200
Price
Order / More Infoalpha-2-macroglobulin (porcine) Antibody from PENINSULA LABORATORIES INTERNATIONAL, INC.
Product Specific Referencesn/a
产品资料