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| Product Name | MNK2, Recombinant, Human, GST-Tag (MAP Kinase-Interacting Kinase 2, MKNK2, GPRK7) |
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| Description | Purified (~70-90%). MNK2 (MAP kinase-interacting kinase 2) contains a conserved C-terminal ERK-interacting domain, a catalytic domain with homology to the calcium/calmodulin-dependent family of kinases, and putative MAP kinase phosphorylation sites located within the T loop of the kinase domain. MNK2 binds tightly to the growth factor-regulated MAP kinases, ERK1 and ERK2. ERK and p38 phosphorylate MNK2, which stimulates its in vitro kinase activity toward a substrate, eukaryotic initiation factor-4E (eIF-4E). A yeast two-hybrid screen showed the Mnk2 protein interacted with the ligand-binding domain of estrogen receptor beta (ERbeta). Source: Recombinant protein corresponding to human MNK2, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~74kD Specific Activity: 93nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_017572 |
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| Catalog # | 500277 |
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| Order / More Info | MNK2, Recombinant, Human, GST-Tag (MAP Kinase-Interacting Kinase 2, MKNK2, GPRK7) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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