产品详情 |
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Product Name | A 971432 |
Description | Potent and selective S1P5 agonist (EC50 values are 4.1 and 5.7 nM in cAMP and GTPγS assays, respectively). Exhibits 60-fold selectivity over S1P1, and >1,600-fold selectivity over S1P2-4, and a panel of 129 kinases and 79 receptors. Improves blood-brain barrier integrity in vitro and reverses age-related cognitive decline in vivo. Orally available. Purity 99%. MW (observed): 366.24 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-[[4-[(3,4-Dichlorophenyl)methoxy]phenyl]methyl]-3-azetidinecarboxylic acid |
Gene, Accession, CAS # | CAS: 1240308-45-5 |
Catalog # | 5766/10 |
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Order / More Info | A 971432 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 30543684 |
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