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| Product Name | FKBP3, Recombinant, Human, aa1-224 (FK506 binding protein 3, FKBP25, PPIase FKBP3, Rotamase) |
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| Description | Purity ~90% (SDS-PAGE). FKBP3 is part of a family of immunosuppressant receptors which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 accelerates the folding of proteins. FKBP3 is part of the immunophilin protein family, which participates in immunoregulation and fundamental cellular processes concerning protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a greater affinity for rapamycin than for FK506 and therefore is a significant protein for immunosuppression by rapamycin. Source: Recombinant protein corresponding to aa1-224 from human FKBP3, expressed in E. coli. Molecular Weight: ~25.1kD (224aa, aa1-224) Specific Activity: >490nmoles/min/mg, defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA/minute at 25°C in Tris HCl pH 8.0 usi |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 169968 |
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| Order / More Info | FKBP3, Recombinant, Human, aa1-224 (FK506 binding protein 3, FKBP25, PPIase FKBP3, Rotamase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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