产品名称 Synaptotagmin 1 Antibody from DIANOVA GmbH
产品货号 SySy105011
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 DIANOVA GmbH
产品概述
产品详情
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Antigenic SpecificitySynaptotagmin 1
Clone41.1
Host SpeciesMouse
Reactive Specieshuman, rat, mouse, zebrafish
IsotypeIgG2a
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsIHC, Paraffin Sections (FFPE), Frozen Sections, Immunoprecipitation, ELISA
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionCa2+ sensor widely expressed in teh nervous system. Synaptotagmin 1 is an integral membrane glycoprotein of neuronal synaptic vesicles and secretory granules of neuroendocrine cells that is widely (but not ubiquitously) expressed in the central and peripheral nervous system. Ca2+-binding to synaptotagmin triggers exocytosis of synaptic vesicles, thus linking Ca2+-influx during depolarization to neurotransmitter release. Synaptotagmin is expressed in mast cells of normal human tissues and potentially involved in histamine release in allergic and asthmatic reactions.
ImmunogenRecombinant protein of rat synaptotagmin 1 (aa 80 - 421) containing the C-terminal part.
Other NamesP65, SVP65, SYT, synaptotagmin 1, synaptotagmin-1, sytI
Gene, Accession #SYT1, 6857
Catalog #SySy105011
Price
Order / More InfoSynaptotagmin 1 Antibody from DIANOVA GmbH
Product Specific ReferencesSynaptic pathology, altered gene expression, and degeneration in photoreceptors impacted by drusen. Johnson PT, Brown MN, Pulliam BC, Anderson DH & Johnson LV. Investigative Ophtalmology and Visual Science 46: 4788-95, 2005. / Brain synaptic junctional proteins at the acrosome of rat testicular germ cells. Redecker P, Kreutz MR, Bockmann J, Gundelfinger ED & Boeckers TM. Journal of Histochemistry and Cytochemistry 51: 809-19, 2003. / Changes in retinal synaptic proteins in the transgenic model expressing a mutant HRG4 (UNC119). Kubota S, Kobayashi A, Mori N, Higashide T, McLaren MJ & Inana G. Investigative Ophtalmology and Visual Science 43: 308-13, 2002. / Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses. von Kriegstein K, Schmitz F, Link E & Sudhof T. European Journal of Neuroscience 11: 1335-48, 1999.
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