产品详情 |
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Antigenic Specificity | SMC1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100µg |
Concentration | n/a |
Applications | ELISA, WB • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:20 - 1:100; IP1:50 - 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-SMC1A polyclonal antibody. Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. Th |
Immunogen | structural maintenance of chromosomes 1A |
Other Names | DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1 |
Gene, Accession # | Gene ID: 8243, UniProt: Q14683 |
Catalog # | FNab08016 |
Price | |
Order / More Info | SMC1A Antibody from FINETEST |
Product Specific References | n/a |
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