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| Product Name | Human IGF-I, recombinant protein (Receptor Grade) |
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| Description | Product Specifications Human IGF-I: Insulin-like growth factor-I (IGF-I) is a 70 amino acid polypeptide that stimulates growth and differentiation in many cell types including rat L6 myoblasts. Link to Sequence:Source: IGF-I is produced in E. coli using a patented expression system and the IGF-I is correctly folded and purified by several chromatography steps to yield Receptor Grade IGF-I.Purity: > 95% (as determined by HPLC and N-terminal sequence analysis)Molecular Weight: 7649 daltons - confirmed by Mass SpectrometryN-terminal sequence analysis of recombinant product: 5 residues >95% single sequenceBiological Activity: (stimulation of protein synthesis in rat L6 myoblasts) ED50 <30 ng/mlEndotoxin (LAL): <0.1 EU/ugStorage/Stability: At least 2 years at 2-4°C (lyophilised)Appearance: White PowderState: Dried from 0.1 M acetic acid: under dry nitrogen at slight vacuum (-25kPa)Reconstitution: Dissolve in dilute acid (e.g. 10mM HCl or 0.1M acetic acid), aliquot and store at -20°C. For lower dilutions (e.g. <1mg/ml) inclusion of a carrier protein is recommended. Avoid freeze-thaw cycles.This is a GroPep specification. ibt is authorized distributor of GroPep Ltd. |
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| Size | 20 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Igf-1, insulin-like growth factor-1, Somatomedin c, ILGF1, Mechano growth factor |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | CU020 CU100 CM001 |
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| Order / More Info | Human IGF-I, recombinant protein (Receptor Grade) from IMMUNOLOGICAL & BIOCHEMICAL TESTSYSTEMS GmbH |
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| Product Specific References | 1. Granata et al. (2007): Insulin-like growth factor binding protein-3 induces angiogenesis through IGF-I- and SphK1-dependent mechanisms. Journal of Thrombosis and Haemostasis. Volume 5, Issue 4, Pages 835-845. Link to Article.2. Ciucci F, Putignano E, Baroncelli L, Landi S, Berardi N, et al. (2007) Insulin-Like Growth Factor 1 (IGF-1) Mediates the Effects of Enriched Environment (EE) on Visual Cortical Development. PLoS ONE 2(5): e475 doi:10.1371/journal.pone.0000475 Link to Article. |
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