产品详情 |
Edit |   |
Antigenic Specificity | AATF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, equine, guinea pig, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AATF Polyclonal Antibody. AATF (apoptosis antagonizing transcription factor) was initially discovered as an interaction partner of ZIP kinase (ZIPK), a member of death-associated protein (DAP) kinase family of pro-apoptotic serine/threonine kinases. AATF is a phosphoprotein containing an acidic region and a putative leucine zipper domain and nuclear localization signal, features which are typical of transcription factors. AATF inhibits the ZIPK-mediated pro-apoptotic pathway and may activate other anti-apoptotic pathways. Recently, it has also been shown to protect neural cells against oxidative damage induced by amyloid b-peptide and to inhibit aberrant production of the beta-peptide by interacting with Par-4 (prostate apoptosis response-4 |
Immunogen | n/a |
Other Names | Apoptosis antagonizing transcription factor, DED, CHE1, CHE-1 |
Gene, Accession # | Entrez: 100057601, 100356226, 100513881, 100732839, 100856664, 114512, 26574, 56321, 786013; Uniprot: Q9JKX4, Q9NY61, Q9QYW0 |
Catalog # | PA5-41534 |
Price | |
Order / More Info | AATF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|