产品详情 |
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Antigenic Specificity | AATF/Che-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunoprecipitation: 2-5 µg/mg lysate |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AATF/Che-1 Polyclonal Antibody. AATF (apoptosis antagonizing transcription factor) was initially discovered as an interaction partner of ZIP kinase (ZIPK), a member of death-associated protein (DAP) kinase family of pro-apoptotic serine/threonine kinases. AATF is a phosphoprotein containing an acidic region and a putative leucine zipper domain and nuclear localization signal, features which are typical of transcription factors. AATF inhibits the ZIPK-mediated pro-apoptotic pathway and may activate other anti-apoptotic pathways. Recently, it has also been shown to protect neural cells against oxidative damage induced by amyloid b-peptide and to inhibit aberrant production of the beta-peptide by interacting with Par-4 (prostate apoptosis resp |
Immunogen | n/a |
Other Names | HSPC277, CHE-1, CHE1, DED; apoptosis-antagonizing transcription factor; protein AATF; rb-binding protein Che-1 |
Gene, Accession # | Entrez: 26574; Uniprot: Q9NY61 |
Catalog # | A301-032A |
Price | |
Order / More Info | AATF/Che-1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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