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| Product Name | pro-IGF-II, Recombinant, Human (Pro-Insulin like Growth Factor-2, pro-IGF2) |
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| Description | Purity ~95% (SDS-PAGE). Insulin-like growth factor 2 (IGF2) is one of the mitogenic, polypeptide growth factors that belongs to the insulin family, due to its structural and functional similarity to insulin. IGF2 is mainly produced in the liver and several other tissues at certain times. IGF2 expression can be found in many tissues usually with autocrine, paracrine and endocrine functions, and mainly acts as a growth promoting hormone during gestation. The pro-IGF-II proteins make up 10-20% of circulating IGF2 and is converted to mature IGF2 by sequential cleavage at 104aa, 87aa, 67aa. Pro-IGF-II proteins are secreted by some tumor cell lines and levels are elevated in non-islet cell tumor hypoglycaemia. Recombiant Human pro-IGF-II is expressed in human 293 cells as a monomeric glycoprotein with a molecular mass of 25kD. Source: Recombinant protein corresponding to human pro-IGF-II expressed in HEK293. Molecular Weight: ~25kD Biological Activity: The EC50 as determined by the dose-dependent stimulation of the |
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| Size | 10ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q13253 |
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| Catalog # | 500410 |
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| Order / More Info | pro-IGF-II, Recombinant, Human (Pro-Insulin like Growth Factor-2, pro-IGF2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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