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Product Name | ABC294640 |
Description | MW: 380.91. Purity ≥98% by HPLC. ABC294640 is a specific spingosine kinase-2 (SK-2) inhibitor having antineoplastic activity. This orally available aryl admantane molecule upon administration binds and inhibits SK-2; preventing phosphorylation of the pro-apoptotic amino alcohol spingosine to spingosine-1-phosphate (S1P); the lipid mediator that is important for immunomodulation; this phosphorylation prevention of amino alcohol can induce apoptosis and may inhibit cancer cell proliferation. |
Size | 5 mg, 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [1S; 3R; 5R; 7S)-3- (4-chlorophenyl)-N- (pyridin-4-ylmethyl) adamantane-1-carboxamide] |
Gene, Accession, CAS # | CAS: 915385-81-8 |
Catalog # | MBS846373 |
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Order / More Info | ABC294640 from MYBIOSOURCE INC. |
Product Specific References | n/a |
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