| 产品详情 |
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| Product Name | ACY-1215 |
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| Description | Purity >98% by HPLC. ACY-1215 is a potent, cell-permeable and selective inhibitor of histone deacetylase 6 (HDAC6) (IC50 = 5 nM). ACY-1215 is 12-, 10-, 11 and 21-fold less active against HDAC1, HDAC2, HDAC3 and HDAC8, respectively. It displays minimal activities (IC50 > 1 µM) against HDAC4, HDAC5, HDAC7, HDAC9, HDAC11, Sirtuin1, and Sirtuin2. In combination with Tubastatin, it improves cognition in Alzheimer's Disease (AD) transgenic mice. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Rocilinostat, 2-(diphenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide, ACT-1215 |
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| Gene, Accession, CAS # | CAS: 1316214-52-4 |
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| Catalog # | LS-H3195 |
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| Order / More Info | ACY-1215 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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