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| Product Name | Semaphorin 3A, Recombinant, Human (SEMA3A, SEMAD) |
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| Description | Purity ~95% (SDS-PAGE). Semaphorins are a large group of structurally related secreted, GPI-anchored and transmembrane cell signaling molecules. There are 8 major classifications (1-7) of Semaphorins characterized by the existence of a conserved 500aa SEMA domain at the amino terminus. Classes 3, 4, 6, and 7 are found in vertebrates only, whilst class 5 is found in both vertebrates and invertebrates. Each class is then divided into additional subgroups based on shared structural characteristics. Semaphorins primarily function as axon growth cone guidance factors during neuronal development. Semaphorin 3A acts as a chemo-repellent to axons, and an inhibitor of the growth of axons by signaling through receptors, Neuropilin-1and Plexin-A. Recombinant human Semaphorin 3A is a 751aa protein containing the SEMA domain, an immunoglobulin c2-like domain and a basic domain (Arg/Lys rich) near the C-terminus. Source: Recombinant protein corresponding to human Semaphorin 3A, expressed in CHO cell |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SEMA3A, SEMAD |
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| Gene, Accession, CAS # | SEMA3A, Gene ID: 10371, SwissProt: Q14563 |
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| Catalog # | 220257 |
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| Order / More Info | Semaphorin 3A, Recombinant, Human (SEMA3A, SEMAD) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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