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| Product Name | Semaphorin 5A, Recombinant, Mouse, Fc Chimera |
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| Description | Purity ~95% (SDS-PAGE). Semaphorin 5A (Sema5A, previously called SemaF) is a 140kD protein of the semaphorin family of axon guidance molecules (1-4). Class 5 semaphorins are type I transmembrane glycoproteins with an N-terminal Sema domain and multiple juxtamembrane type 1 thrombospondin (TSP) repeats within their extracellular domains (1-3). Sema5A is expressed developmentally in oligodendrocytes, neuroepithelial cells surrounding retinal axons, the base of limb buds, the cardiac atrial septum and endocardial cushions, and the mesoderm surrounding cranial vessels (3-6). The mouse Sema5A cDNA encodes a 22aa signal sequence, a 946 aa extracellular domain (ECD), a 24 aa transmembrane sequence and an 85 aa cytoplasmic portion. Within aa 23-765, which includes the sema domain and four of the seven TSP repeats, mouse Sema5A shares 93%, 98%, 93%, 92% and 91% aa identity with corresponding human, rat, porcine, bovine and canine sequences. Semaphorins typically transduce signals through transm |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Semaphorin 5A, Recombinant, Mouse, Fc Chimera (Semaphorin-5A, Semaphorin-F, Sema F, Sema5a, Semaf, SemF) |
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| Gene, Accession, CAS # | Accession: NP_033180 |
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| Catalog # | S0668-58 |
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| Order / More Info | Semaphorin 5A, Recombinant, Mouse, Fc Chimera from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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