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Product Name | ARPP19, 1-112aa, Human, His tag, E.coli |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol. cAMP-regulated phosphoprotein 19, also known as ARPP19, is protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. This protein may indirectly enhance GAP-43 expression. Recombinant human ARPP19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | cAMP-regulated phosphoprotein 19, cAMP-regulated phosphoprotein 19, ARPP-16, ARPP-19, ARPP16, ENSAL |
Gene, Accession, CAS # | NP 006619 |
Catalog # | ATGP2449 |
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Order / More Info | ARPP19, 1-112aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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