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| Product Name | PAI1, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE, HPLC). Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. They are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SERPINE1 and PLANH1, is a secreted protein which belongs to the serpin family. SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. Defects in SERPINE1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SERPINE1 defect in |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PAI1, Recombinant, Human (Serpin E1, PAI-1, Plasminogen Activator Inhibitor 1, PAI, Endothelial Plasminogen Activator Inhibitor) |
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| Gene, Accession, CAS # | SERPINE1, Gene ID: 5054, SwissProt: P05121 |
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| Catalog # | 220128 |
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| Price | |
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| Order / More Info | PAI1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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