| 产品详情 |
| Edit |   |
|---|
| Product Name | PAI-1, Recombinant, Human, aa24-402, His-Tag |
|---|
| Description | Purity ~95% (SDS-PAGE). Plasminogen activator inhibitor-1 is the principal inhibitor of tissue plasminogen activator (tPA) and Urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots). It is a serine protease inhibitor (serpin) protein (SERPINE1). The other PAI, plasminogen activator inhibitor-2 (PAI-2) is secreted by the placenta and only present in significant amounts during pregnancy. In addition, protease nexin acts as an inhibitor of tPA and urokinase. SERPINE1, however, is the main inhibitor of the plasminogen activators. Recombinant protein corresponding to aa24-402 from PAI-1, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~45kD (400aa, aa24-402 + NT His-Tag) Biological Activity: Specific activity, the IC50 value is <56nm. Measured by its ability to inhibit uPA cleavage of the substrate Z-GGR-AMC. AA Sequence: MGSSHHHHHH SSGLVPRGSH MVHHPPSYVA HLASDFGVRV FQQVAQASKD RNVVFSPYGV ASVLAMLQLT TGGETQQQIQ |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | PAI-1, Recombinant, Human, aa24-402, His-Tag (Plasminogen activator inhibitor-1, SERPINE1, PAI, PAI1, PLANH1) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 170035 |
|---|
| Price | |
|---|
| Order / More Info | PAI-1, Recombinant, Human, aa24-402, His-Tag from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|