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| Product Name | Histone H4, acetylated (Lys8) (Biotin) |
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| Description | Purity 80-90% as detemined by HPLC analysis. Sequence (linear): SGRGKGGAcKGLGKGGAKRHRC-GSGSK-Biotin, which corresponds to the N terminal sequence of histone H4 acetylated at position 8. Application(s): Used to measure histone acetyltransferase (HAT) activity. May be acetylated by HAT on lysines at position 5, 12 and 16. Can be used to determine the preferred acetylation site by any particular HAT that acetylates histone H4, when used with peptides of identical sequence but differing acetylated lysine residues. Dot Blot: Used as a standard to assess the specificity of anti-acetyl histone antibodies for acetyl lysine 8 of Histone H4. Autoantibodies to histone antigens have been described in patients with idiopathic and drug-induced SLE, rheumatoid arthritis, and other conditions. The presence of autoantibodies to histones are frequently found in several rheumatic disorders (1). In one study, the predominant responses to histones in SLE sera were to H1, H2b, and H3. Marked elevations of b |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | DB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | H5110-15L1 |
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| Price | |
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| Order / More Info | Histone H4, acetylated (Lys8) (Biotin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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