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| Product Name | GTF2E2, Recombinant, Human, aa1-291, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). GTF2E2, also known as TFIIE, is essential for transcription initiation by RNA polymerase II in conjunction with other general factors. TFIIE is a heterotetramer containing two subunits of relative molecular mass 57,000 (TFIIE-alpha) and two of 34,000 (TFIIE-beta). TFIIE-beta is required in conjunction with TFIIE-alpha for transcription initiation. GTF2E2 recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. Source: Recombinant corresponding to aa1-291 from human GTF2E2, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~35.6kD (315aa) confirmed by MALDI-TOF AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMDPSLL RERELFKKRA LSTPVVEKRS ASSESSSSSS KKKKTKVEHG GSSGSKQNSD HSNGSFNLKA LSGSSGYKFG VLAKIVNYMK TRHQRGDTHP LTLDEILDET QHLDIGLKQK QWLMTEALVN NPKIEVIDGK YAFKPKYNVR DKKALLRLLD QHDQRGLGG |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GTF2E2, Recombinant, Human, aa1-291, His-Tag (Transcription Initiation Factor IIE Subunit beta, TFIIE-beta, General Transcription Factor IIE Subunit 2, TF2E2) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45431 |
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| Order / More Info | GTF2E2, Recombinant, Human, aa1-291, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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