| 产品详情 |
| Edit |   |
|---|
| Product Name | MNK1/2 Inhibitor II, ETP-45835 |
|---|
| Description | Purity ~98% (HPLC). A cell-permeable 3,5-disubstituted pyrazolo compound that acts as a selective MNK inhibitor (IC50=646 and 575nM, respectively, against MNK1 and MNK2) with much reduced or little activity against 24 other kinases (100uM at pH 7.4) and inhibit the proliferation (IC50=17uM) and cellular eIF4E Ser209 phosphorylation (IC50=4.7uM) of MV4:11 cells. Formula: C13H16N4 · 2HCl Solubility: H2O Molecular Weight: 301.2 |
|---|
| Size | 10mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | MNK1/2 Inhibitor II, ETP-45835 (ETP45835?MNK Inhibitor II, Mitogen-Activated Protein Kinase-Interacting Kinase Inhibitor II) (4-(3-(Piperidin-4-yl)-1H-pyrazol-5-yl)pyridine, diHCl) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 217563 |
|---|
| Price | |
|---|
| Order / More Info | MNK1/2 Inhibitor II, ETP-45835 from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|