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Product Name | ABT 089 dihydrochloride |
Description | High affinity and selective α4β2 partial agonist (Ki = 16 nM). Exhibits >1000-fold and >10,000-fold selectivity for α4β2 over α1β1γ1 and α7 receptors respectively. Neuroprotective against glutamate-induced toxicity in rat cortical neurons in vitro. Enhances cognitive performance in vivo. Orally bioavailable and brain penetrant. Purity 98%. MW (observed): 265.18 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride |
Gene, Accession, CAS # | CAS: 161416-61-1 |
Catalog # | 5079/10 |
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Order / More Info | ABT 089 dihydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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