| 产品详情 |
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| Product Name | JNJ-10198409 |
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| Description | Purity >98%. Inhibition of the tyrosine kinase activity of growth factor receptors such as the platelet-derived growth factor (PDGF-BB) receptor can have potent antiangiogenic and antiproliferative activity. JNJ-10198409 is a small molecule inhibitor of platelet-derived growth factor (PDGF-BB) tyrosine kinase with an IC50 value of 4.2 nM when tested in human coronary artery smooth muscle cells. JNJ-10198409 is a competitive antagonist of the ATP binding and hydrolysis at this receptor, resulting in a dose dependent inhibition of tumor growth and angiogenesis. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(3-fluorophenyl)-1,4-dihydro-6,7-dimethoxy-indeno[1,2-c]pyrazol-3-amine |
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| Gene, Accession, CAS # | CAS: 627518-40-5 |
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| Catalog # | LS-H8290 |
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| Order / More Info | JNJ-10198409 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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