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Haptoglobin, Human, Phenotype 2-2 (Alpha Polypeptide, HP, Hp2 alpha, Beta Polypeptide, HPT, HPA1S, HP2 alpha2) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | Haptoglobin, Human, Phenotype 2-2 (Alpha Polypeptide, HP, Hp2 alpha, Beta Polypeptide, HPT, HPA1S, HP2 alpha2) |
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| Description | Purity ≥95% (SDS-PAGE). No visible alpha-1 light chain. An acute-phase plasma protein found in human plasma at 100-300mg/100ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes. Hp 1-1 is the most common, and the most effective in binding free hemoglobin. Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype. Hp 2-2 is associated with renal failure, familial epilepsy, hypertension, atherosclerosis and coronary heart diseases. Individuals who are phenotype 2-2 have the lowest concentration of haptoglobin in plasma. Source: Native Haptoglobin, from human plasma Purity: ≥95% (SDS-PAGE). No visible alpha-1 light chain. Molecular Weight:: 170,000-900,000 Extinction Coefficient: 1.20 Source: Native Source: Native |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 301367 |
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| Order / More Info | Haptoglobin, Human, Phenotype 2-2 (Alpha Polypeptide, HP, Hp2 alpha, Beta Polypeptide, HPT, HPA1S, HP2 alpha2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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