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| Product Name | Haptoglobin, Human Plasma (Mixed Type) (Haptoglobin B-Chain, Haptoglobin A-chain, Hp, Bp) |
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| Description | Purity ~95% (SDS-PAGE). An acute-phase plasma protein found in human plasma at 100-300mg per 100ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes: Hp 1-1, Hp 2-1, and Hp 2-2. While the phenotypic distribution can vary greatly between ethnicities and geographic location, the Hp 2-1 phenotype is the most prevalent phenotype in humans. Plasma concentrations of haptoglobin are highest in individuals with Hp 1-1, intermediate in Hp 2-1 individuals, and lowest in Hp 2-2 individuals. Hp 1-1 is the most effective at binding hemoglobin, and Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype. Source: Haptoglobin, from Human Plasma Molecular Weight: Hp 1-1: 86kD; Hp 2-1: 200kD; Hp 2-2: 400kD |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | HP, Gene ID: 3240, SwissProt: P00738 |
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| Catalog # | 301227 |
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| Order / More Info | Haptoglobin, Human Plasma (Mixed Type) (Haptoglobin B-Chain, Haptoglobin A-chain, Hp, Bp) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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