| 产品详情 |
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| Product Name | Hepcidin, 25aa, oxidized, Mouse, Control Peptide |
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| Description | Purity ≥ 95% by HPLC. Hepcidin (Hepc, hepatic bactericidal protein) or LEAP (liver expressed antimicrobial peptide) is small, cysteine-rich peptide, antimicrobial peptide similar to defensins and thionins. Hepcidin (unprocessed, proprotein in mouse 83 aa, rat/human 84 aa) are almost exclusively produced in liver. Human hepcidin is produced from 84-aa precursor, including a putative 24-aa signal peptide. The secreted form of hepcidin in blood and urine is consists of C-terminal 20, 22 or 25-aa residues in humans and 25-aa in mouse. In humans, 20-aa and 25-aa appears to be the major HEPC secreted peptides with antimicrobial activities. The three secreted HEPC alternatively spliced HEPC peptides differ at the N-terminus. Human DTHFP ICIFC CGCCH RSKCG MCCKT (25-aa) ICIFC CGCCH RSKCG MCCKT (20-aa) Mouse DTNFP ICIFC CKCCN NSQCG ICCKT (25 aa) 4 cys-Cys bridges The link between hepcidins and iron metabolism is that hepcidin expression is abolished in mice exhibiting iron-overload due to the ta |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Hepcidin, 25aa, oxidized, Mouse, Control Peptide (Hepc, LEAP, Hepatic Bactericidal Protein, Liver Expressed Antimicrobial Peptide) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | H2008-55A |
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| Order / More Info | Hepcidin, 25aa, oxidized, Mouse, Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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