| 产品详情 |
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| Product Name | Hepcidin, Human, 20aa, Control Peptide |
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| Description | Purity ≥ 95% (HPLC). Hepcidin (Hepc , hepatic bactericidal protein) or LEAP (liver expressed antimicrobial peptide) is small, cysteine-rich peptide, antimicrobial peptide similar to defensins and thionins. Hepcidin (unprocessed, proprotein in mouse 83aa, rat/human 84aa) are almost exclusively produced in liver. Human hepcidin is produced from 84aa precursor, including a putative 24aa signal peptide. The secreted form of hepcidin in blood and urine is consists of C-terminal 20, 22 or 25aa residues in humans and 25aa in mouse. In humans, 20aa and 25aa appears to be the major HEPC secreted peptides with antimicrobial activities. The three secreted HEPC alternatively spliced HEPC peptides differ at the N-terminus. Biological or antimicrobial activities of this HEPC peptide has not been studied. The link between hepcidins and iron metabolism is that hepcidin expression is abolished in mice exhibiting iron-overload due to the targeted disruption of USF2 (upstream stimulatory factor 2) gene r |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Hepcidin, Human, 20aa, Control Peptide (Hepc, LEAP, Hepatic Bactericidal Protein, Liver Expressed Antimicrobial Peptide) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | H2008-57 |
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| Order / More Info | Hepcidin, Human, 20aa, Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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