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| Product Name | Phosphogluconate Dehydrogenase, Recombinant, Human |
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| Description | Purity ~ 95% (SDS-PAGE). Purified by using conventional chromatography techniques. PGD (Phosphogluconate dehydrogenas), also known as 6PGD, is a 483 amino acid enzyme that is involved in the pentose phosphate shunt. Pentose is required for nucleic acid biosynthesis and the pentose phosphate cycle is a major source of NADPH. PGD deficiency increases the level of erythrocyte pyruvate kinase (PK) activity and reduces glutathione synthetase (GSH), resulting in hemolysis. Defects in PGD are generally asymptomatic and are inherited in an autosomal dominant fashion. Recombinant protein corresponding to human PGD, fused to His-tag at N-terminus, was expressed in E. coli (NP_002622). AA Sequence: MGSSHHHHHH SSGLVPRGSH MAQADIALIG LAVMGQNLIL NMNDHGFVVC AFNRTVSKVD DFLANEAKGT KVVGAQSLKE MVSKLKKPRR IILLVKAGQA VDDFIEKLVP LLDTGDIIID GGNSEYRDTT RRCRDLKAKG ILFVGSGVSG GEEGARYGPS LMPGGNKEAW PHIKTIFQGI AAKVGTGEPC CDWVGDEGAG HFVKMVHNGI EYGDMQLICE AYHLMKDVLG MAQDEMAQAF EDWNKTELDS FLIEITANIL KFQDTDGKHL LPKIRD |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Phosphogluconate Dehydrogenase, Recombinant, Human (PGD, PGDH, 6PGD, 6-Phosphogluconate Dehydrogenase (Decarboxylating)) |
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| Gene, Accession, CAS # | Accession: NP_002622 |
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| Catalog # | P4073-07H |
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| Order / More Info | Phosphogluconate Dehydrogenase, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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